Imperial College London

MARPLE (MagMove Assisted RNA Purification and Lateral flow Evaluation) is an innovative point-of-care diagnostic platform designed to rapidly and accurately differentiate between bacterial and viral infections. Using patent-protected mRNA biomarkers, MARPLE provides results in under 10 minutes from a small blood sample, enabling timely and precise clinical decision-making. The DETECTIVE project focuses on optimising MARPLE’s diagnostic accuracy, validating its performance with clinical samples, and ensuring it is affordable, user-friendly, and scalable for use in NHS A&E departments. By reducing unnecessary antibiotic prescriptions, MARPLE addresses the global challenge of antimicrobial resistance while improving patient care.