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ProReal has developed an avatar-based, virtual-world software platform, which early evidence suggests can deliver effective mental health interventions for people with mood disorders such as anxiety, depression and trauma. As an online representation of the user’s world, the technology supports self-expression, affect labelling and regulation, thereby reducing levels of psychological distress and providing a more accessible pathway to treatment for young people in particular.

Mayden has developed Prism, a cloud based hub to enable NHS Improving Access to Psychological Therapy (IAPT) patients to be referred for online therapy, with progress notes received seamlessly and securely back into the patient record. This means that patients can access therapy more quickly, from home, at a time that suits them.

P1vital has developed a machine learning based online app, the PReDicT Test, designed for patients with depression to predict early in treatment whether their antidepressant is working. Antidepressants are widely prescribed but take 4-6 weeks before patients feel better with two thirds of patients not responding to the first drug prescribed. Identifying an effective antidepressant within days not months provides benefit to millions of patients and reduces the economic burden of depression which costs the NHS and the wider economy over £11bn/yr.